Letrozole Drug Description

Letrozole is a medication primarily used in the treatment of breast cancer, particularly in postmenopausal women. It belongs to a class of drugs known as aromatase inhibitors, which work by decreasing estrogen production in the body. This reduction in estrogen can help slow or reverse the growth of certain types of breast tumors that require estrogen to grow.

Mechanism of Action

Letrozole inhibits the aromatase enzyme, which is responsible for converting androgens into Letrozol Labatec 2.5mg drug description estrogens. By blocking this enzyme, letrozole lowers estrogen levels in the body, making it less likely for estrogen-dependent tumors to thrive.

Indications

• Treatment of hormone receptor-positive breast cancer in postmenopausal women.
• Adjuvant therapy following surgery and radiation.
• Treatment of advanced breast cancer in combination with other therapies.

Dosage and Administration

The recommended dosage of letrozole typically involves:

1. One 2.5 mg tablet taken orally once daily.
2. Can be taken with or without food.
3. Duration of treatment varies depending on individual cases and should be guided by a healthcare provider.

Side Effects

Common side effects associated with letrozole include:

• Hot flashes
• Joint pain or stiffness
• Fatigue
• Nausea
• Headache

Serious side effects may also occur, such as:

• Bone thinning (osteoporosis)
• Heart problems
• Severe allergic reactions

Precautions

Before starting letrozole, patients should inform their doctor if they have:

• A history of heart disease.
• Osteoporosis or risk factors for bone loss.
• Allergies to any medications.

FAQs about Letrozole

What should I do if I miss a dose of letrozole?

If you miss a dose, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose and resume your regular schedule. Do not double up on doses.

Can letrozole be used in premenopausal women?

No, letrozole is specifically indicated for postmenopausal women. Premenopausal women should discuss alternative treatments with their healthcare provider.

How long can I expect to be on letrozole?

The duration of treatment varies by individual, but it is often recommended for at least five years, depending on the response to therapy and the judgment of the treating physician.

Conclusion

In summary, letrozole is an effective medication for the treatment of certain types of breast cancer in postmenopausal women. Understanding its mechanism of action, proper administration, potential side effects, and precautions can help patients manage their treatment effectively. Always consult with a healthcare provider for personalized medical advice regarding use and dosage.